ⓘ Free online encyclopedia. Did you know? page 227




                                               

PLCE1

1-Phosphatidylinositol-4.5-bisphosphate phosphodiesterase epsilon-1 is an enzyme that in humans is encoded by the PLCE1 gene. This gene encodes a phospholipase enzyme that catalyzes the hydrolysis of phosphatidylinositol-4.5-bisphosphate to gener ...

                                               

Pleckstrin homology domain containing S1

                                               

PLEKHA1

                                               

PLXDC2

                                               

PPAPDC1A

Phosphatidate phosphatase PPAPDC1A also known as phosphatidic acid phosphatase type 2 domain containing 1A is an enzyme that in humans is encoded by the PPAPDC1A gene. PPAPDC1A has phosphatidate phosphatase activity.

                                               

PPIF

Peptidyl-prolyl cis-trans isomerase, mitochondrial is an enzyme that in humans is encoded by the PPIF gene. It has also been referred to as, but should not be confused with, cyclophilin D, which is encoded by the PPID gene. As a member of the pep ...

                                               

PPP2R2D

PP2A subunit B isoform delta also known as serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform is a protein that in humans is encoded by the PPP2R2D gene. It is a regulatory subunit of the heterotrimeric protein phos ...

                                               

PPP3CB

                                               

PPRC1

Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 is a protein that in humans is encoded by the PPRC1 gene. The protein encoded by this gene, similar RAPP-gamma coactivator 1 PPARGC1 / NTC-1, a protein that can activa ...

                                               

PRAP1

                                               

PRDX3

Thioredoxin-dependent peroxide reductase, mitochondrial is an enzyme that in humans is encoded by the PRDX3 gene. It is a member of the peroxiredoxin family of antioxidant enzymes.

                                               

PRKCQ

Protein kinase C theta is an enzyme that in humans is encoded by the PRKCQ gene. PKC-θ, a member of serine/threonine kinases, is mainly expressed in hematopoietic cells with high levels in platelets and T lymphocytes, where plays a role in signal ...

                                               

PRKG1

                                               

Protein DEPP

Protein DEPP also known as decidual protein induced by progesterone and fasting-induced gene protein is a protein that in humans is encoded by the DEPP gene.

                                               

PTF1A

This gene encodes a protein that is a component of the pancreas transcription factor 1 complex PTF1 and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic ...

                                               

PTPRE

The protein encoded by this gene is a member of the protein tyrosine phosphatase PTP family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogen ...

                                               

RAB11FIP2

                                               

RAB18

Ras-related protein Rab-18 is a protein that in humans is encoded by the RAB18 gene. Rab18 is ubiquitously expressed protein with high expression level in the brain. Rab18 was first characterized as an endosomal protein in epithelial cells of mou ...

                                               

RASGEF1A

                                               

RBM17

                                               

RBP3

Retinol-binding protein 3, interstitial, also known as IRBP is a protein that in humans is encoded by the RBP3 gene. RBP3 orthologs have been identified in most eutherians except tenrecs and armadillos.

                                               

Redox-regulatory protein FAM213A

Redox-regulatory protein FAM213A also known as peroxiredoxin-like 2 activated in M-CSF stimulated monocytes is a protein that in humans is encoded by the FAM213A gene.

                                               

Renalase

Renalase, FAD-dependent amine oxidase is an enzyme that in humans is encoded by the RNLS gene. Renalase is a flavin adenine dinucleotide-dependent amine oxidase that is secreted into the blood from the kidney.

                                               

RGS10

Regulator of G protein signaling RGS family members are regulatory molecules that act as GTPase activating proteins GAPs for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go ...

                                               

Rho gtpase activating protein 21

ARHGAP21 functions preferentially as a GTPase-activating protein GAP for CDC42 MIM 116952 and regulates the ARP2/3 complex MIM 604221 and F-actin dynamics at the Golgi through control of CDC42 activity Dubois et al., 2005.

                                               

RHOBTB1

Rho-related BTB domain-containing protein 1 is a protein that in humans is encoded by the RHOBTB1 gene. The protein encoded by this gene belongs to the family Ro RAS superfamily of small GTPase. It contains domain GTP-Aza, and the Proline-rich re ...

                                               

RPP30

                                               

RPP38

                                               

RRP12

RRP12-like protein is a protein that in humans is encoded by the RRP12 gene. It is currently thought to be involved in ribosome assembly of the precursor particles of both subunits in eukaryotes and was identified as a RNA binding protein.

                                               

RSU1

Ras suppressor protein 1 is a protein that in humans is encoded by the RSU1 gene. This gene encodes a protein that participates in the transmission path of the signal RAS, growth inhibition, and nerve-growth factor induced differentiation process ...

                                               

RTKN2

                                               

SEC23IP

SEC23-interacting protein is a protein that in humans is encoded by the SEC23IP gene. COPII-coated vesicles involved in protein transport from endoplasmic reticulum to Golgi apparatus. The protein encoded by this gene was identified by its intera ...

                                               

SEC24C

The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex resp ...

                                               

Selenophosphate synthetase 1

Selenide, water dikinase 1 is an enzyme that in humans is encoded by the SEPHS1 gene. This protein encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, ...

                                               

SEMA4G

Semaphorin-4G is a protein that in humans is encoded by the SEMA4G gene. Semaphorins, a large family of conserved secreted and membrane proteins associated, which have semaphoring SEMA domain and psi domain found in plexins, semaphorins and integ ...

                                               

Serglycin

Serglycin, also known as hematopoetic proteoglycan core protein or secretory granule proteoglycan core protein, is a protein that in humans is encoded by the SRGN gene. It is primarily expressed in hematopoietic cells and endothelial cells, and i ...

                                               

SFRP5

Secreted frizzled-related protein 5 is a protein that in humans is encoded by the SFRP5 gene. Secreted Frizzled-related protein 5 SFRP5 is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt signaling p ...

                                               

SGMS1

Model organisms have been used in the study of SGMS1 function. A conditional knockout mouse line called Sgms1 tm1aEUCOMMWtsi was generated at the Wellcome Trust Sanger Institute. Male and female animals underwent a standardized phenotypic screen ...

                                               

SGPL1

                                               

SH3PXD2A

                                               

SHOC2

Leucine-rich repeat protein SHOC-2 is a protein that in humans is encoded by the SHOC2 gene. Mutations that result in lipidation of SHOC2 can cause Noonan syndrome.

                                               

Shootin 1

                                               

Signal transducing adaptor molecule

This gene was identified by the rapid tyrosine-phosphorylation of its product in response to cytokine stimulation. The encoded protein contains an SH3 domain and the immunoreceptor tyrosine-based activation motif ITAM. This protein associates wit ...

                                               

SLK (gene)

                                               

Solute carrier family 16 member 12

This gene encodes a transmembrane transporter that likely plays a role in monocarboxylic acid transport. A mutation in this gene has been associated with juvenile cataracts with microcornea and renal glucosuria.

                                               

SORBS1

CAP/Ponsin protein, also known as Sorbin and SH3 domain-containing protein 1 is a protein that in humans is encoded by the SORBS1 gene. CAP/Ponsin is part of a small family of adaptor proteins that regulate cell adhesion, growth factor signaling ...

                                               

SPOCK2

Proteoglycans, which consist of a core protein and covalently linked glycosaminoglycans, are components of the extracellular matrix. SPOCK2 encodes a member of a novel Ca2+-binding proteoglycan family.

                                               

ST8SIA6

Sialic acid is a key determinate of oligosaccharide structures involved in cell-cell communication, cell-substrate interaction, adhesion, and protein targeting. ST8SIA6 belongs to a family of sialyltransferases EC 2.4.99.8 that synthesize sialylg ...

                                               

STAMBPL1

                                               

Stearoyl-CoA desaturase-1

Stearoyl-CoA desaturase is an endoplasmic reticulum enzyme that catalyzes the rate-limiting step in the formation of monounsaturated fatty acids, specifically oleate and palmitoleate from stearoyl-CoA and palmitoyl-CoA. Oleate and palmitoleate ar ...