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MiR-146

miR-146 is a family of microRNA precursors found in mammals, including humans. The ~22 nucleotide mature miRNA sequence is excised from the precursor hairpin by the enzyme Dicer. This sequence then associates with RISC which effects RNA interfere ...

                                               

MIR1271

microRNAs miRNAs are short 20-24 nt non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymer ...

                                               

MOCS2

Molybdenum cofactor synthesis protein 2A and molybdenum cofactor synthesis protein 2B are a pair of proteins that in humans are encoded from the same MOCS2 gene. These two proteins dimerize to form molybdopterin synthase.

                                               

MSH3

DNA mismatch repair protein, MutS Homolog 3 is a human homologue of the bacterial mismatch repair protein MutS that participates in the mismatch repair system. MSH3 typically forms the heterodimer MutSβ with MSH2 in order to correct long insertio ...

                                               

MTMR12

Phosphatidylinositide 3-kinase-derived membrane-anchored phosphatidylinositides, such as phosphatidylinositol 3-phosphate PtdIns3P), regulate diverse cellular processes. The protein encoded by this gene functions as an adaptor subunit in a comple ...

                                               

MTRR (gene)

Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cobalamin co ...

                                               

MYO10

Myosin X, also known as MYO10, is a protein that in humans is encoded by the MYO10 gene. Myosin x is an actin-motor protein to bind to the tips of filopodia.

                                               

Na-K-Cl cotransporter

The Na-K-Cl cotransporter is a protein that aids in the secondary active transport of sodium, potassium, and chloride into cells. In humans there are two isoforms of this membrane transport protein, NKCC1 and NKCC2, encoded by two different genes ...

                                               

NDFIP1

The protein encoded by this gene belongs to a small group of evolutionarily conserved proteins with three transmembrane domains. It is a potential target for ubiquitination by the Nedd4 family of proteins. This protein is thought to be part of a ...

                                               

NDUFAF2

NADH:ubiquinone oxidoreductase complex assembly factor 2, also known as B17.2L or NDUFA12L is a protein that in humans is encoded by the NDUFAF2, or B17.2L, gene. The NDUFAF2 protein is a chaperone involved in the assembly of NADH dehydrogenase a ...

                                               

NIPBL

Nipped-B-like protein, also known as Scc2 or delangin is a protein that in humans is encoded by the NIPBL gene. Nipbl is required for the association of cohesin with DNA and is the major subunit of the cohesin loading complex. Heterozygous mutati ...

                                               

NLN (gene)

Neurolysin, mitochondrial is a protein that in humans is encoded by the NLN gene. It is a 78-kDa enzyme, widely distributed in mammalian tissues and found in various subcellular locations that vary with cell type. Neurolysin exemplifies the abili ...

                                               

NNT (gene)

NAD transhydrogenase, mitochondrial is an enzyme that in humans is encoded by the NNT gene on chromosome 5. NNT gene contains 26 exons and encodes transhydrogenase protein, which is ~109 KDA molecular weight and is involved in antioxidant defense ...

                                               

NOLA2

H/ACA ribonucleoprotein complex subunit 2 is a protein that in humans is encoded by the NHP2 gene. This gene is a member of the H / ACA snoRNPs small nucleolar ribonucleoproteins genetic family. snoRNPs are involved in various aspects of processi ...

                                               

NPM1

NPM1 is associated with nucleolar ribonucleoprotein structures and binds single-stranded and double-stranded nucleic acids, but it binds preferentially G-quadruplex forming nucleic acids. It is involved in the biogenesis of ribosomes and may assi ...

                                               

NSD1

NSD1 is a transcription coregulator protein that encodes Histone Methyltransferase and is associated with Sotos syndrome and Weaver syndrome.

                                               

Nucleoporin 155

Nucleoporin 155 is a protein that in humans is encoded by the NUP155 gene. Nucleoporins are the main components of the nuclear pore complex NPC of eukaryotic cells. They are involved in bilateral trade of molecules, especially mRNAs and proteins ...

                                               

NUDT12

Peroxisomal NADH pyrophosphatase NUDT12 is an enzyme that in humans is encoded by the NUDT12 gene. Nucleotides are involved in many biochemical reactions and pathways within the cell as substrates, cofactors and effectors. Nudix hydrolases, such ...

                                               

Occludin

Occludin is a protein that in humans is encoded by the OCLN gene. Occludin is a 65-kDa integral plasma-membrane protein located at the tight junctions, described for the first time in 1993 by Shoichiro Tsukita. Together with the Claudin group of ...

                                               

Oncostatin M receptor

Oncostatin-M specific receptor subunit beta also known as the Oncostatin M receptor, is one of the receptor proteins for oncostatin M, that in humans is encoded by the OSMR gene. OSMR-member of type I cytokine receptor family. This protein hetero ...

                                               

OR2V2

Olfactory receptor 2V2 is a protein that in humans is encoded by the OR2V2 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

                                               

OR2Y1

Olfactory receptor 2Y1 is a protein that in humans is encoded by the OR2Y1 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory receptor pr ...

                                               

OR4F3

Olfactory receptor 4F3/4F16/4F29 is a protein that in humans is encoded by the OR4F3 gene. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. In the olfactory r ...

                                               

OXCT1

3-oxoacid CoA-transferase 1 is an enzyme that in humans is encoded by the OXCT1 gene. It is also known as succinyl-CoA-3-oxaloacid CoA transferase. Mutations in this gene are associated with succinyl-CoA:3-oxoacid CoA transferase deficiency.

                                               

P4HA2

Prolyl 4-hydroxylase subunit alpha-2 is an enzyme that in humans is encoded by the P4HA2 gene. This gene encodes a component of prolyl-4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunit ...

                                               

PCDH1

Protocadherin-1 is a protein that in humans is encoded by the PCDH1 gene. This gene belongs to the protocadherin subfamily of cadherin superfamily in. The encoded protein is a membrane protein found at cell-cell borders. He is involved in neural ...

                                               

PCDH12

Protocadherin-12 is a protein that in humans is encoded by the PCDH12 gene. This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 6 cadherin ...

                                               

PCDHA2

Protocadherin alpha-2 is a protein that in humans is encoded by the PCDHA2 gene. This gene is a member of the cluster of protocadherin alpha gene, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual g ...

                                               

PCDHA3

Protocadherin alpha-3 is a protein that in humans is encoded by the PCDHA3 gene. This gene is a member of the cluster of protocadherin alpha gene, one of three related gene clusters, tandemly linked on chromosome 5, which demonstrate an unusual g ...

                                               

PCDHA4

Protocadherin alpha-4 is a protein that in humans is encoded by the PCDHA4 gene. This gene is a member of the cluster of protocadherin alpha gene, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual g ...

                                               

PCDHA5

Protocadherin alpha-5 is a protein that in humans is encoded by the PCDHA5 gene. This gene is a member of the cluster of protocadherin alpha gene, one of three related gene clusters, tandemly linked on chromosome 5, which demonstrate an unusual g ...

                                               

PCDHA6

Protocadherin alpha-6 is a protein that in humans is encoded by the PCDHA6 gene. This gene is a member of the cluster of protocadherin alpha gene, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual g ...

                                               

PCDHA9

Protocadherin alpha-9 is a protein that in humans is encoded by the PCDHA9 gene. This gene is a member of the cluster of protocadherin alpha gene, one of three related gene clusters, tandemly linked on chromosome 5, which demonstrate an unusual g ...

                                               

PCDHAC2

Protocadherin alpha-C2 is a protein that in humans is encoded by the PCDHAC2 gene. This gene is a member of the cluster of protocadherin alpha gene, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual ...

                                               

PCDHB2

Protocadherin beta-2 is a protein that in humans is encoded by the PCDHB2 gene. This gene is a member of the protocadherin beta gene cluster one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an u ...

                                               

PCDHB3

Protocadherin beta-3 is a protein that in humans is encoded by the PCDHB3 gene. This gene is a member of the protocadherin beta gene cluster one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an u ...

                                               

PCDHB4

Protocadherin beta-4 is a protein that in humans is encoded by the PCDHB4 gene. This gene is a member of the protocadherin beta gene cluster one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an u ...

                                               

PCDHB5

Protocadherin beta-5 is a protein that in humans is encoded by the PCDHB5 gene. This gene is a member of the protocadherin beta gene cluster one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an u ...

                                               

PCDHB7

Protocadherin beta-7 is a protein that in humans is encoded by the PCDHB7 gene. This gene is a member of the protocadherin beta gene cluster one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an u ...

                                               

PCDHB11

Protocadherin beta-11 is a protein that in humans is encoded by the PCDHB11 gene. This gene is a member of the protocadherin beta gene cluster one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an ...

                                               

PCDHB12

Protocadherin beta-12 is a protein that in humans is encoded by the PCDHB12 gene. This gene is a member of the protocadherin beta gene cluster one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an ...

                                               

PCDHB13

This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene ...

                                               

PCDHB14

Protocadherin beta-14 is a protein that in humans is encoded by the PCDHB14 gene. This gene is a member of the protocadherin beta gene cluster one of three related gene clusters tandemly linked on chromosome 5. The gene clusters demonstrate an un ...

                                               

PCDHB15

Protocadherin beta-15 is a protein that in humans is encoded by the PCDHB15 gene. This gene is a member of the protocadherin beta gene cluster one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an ...

                                               

PCDHB16

Protocadherin beta-16 is a protein that in humans is encoded by the PCDHB16 gene. This gene is a member of the protocadherin beta gene cluster one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an ...

                                               

PCDHGA11

Protocadherin gamma-A11 is a protein that in humans is encoded by the PCDHGA11 gene. This gene is a member of the protocadherin gamma gene cluster one of three related clusters tandemly linked on chromosome 5. These gene clusters have an immunogl ...

                                               

PCDHGA12

Protocadherin gamma-A12 is a protein that in humans is encoded by the PCDHGA12 gene. This gene is a member of the protocadherin gamma gene cluster one of three related clusters tandemly linked on chromosome five. These gene clusters have an immun ...

                                               

PCDHGB7

Protocadherin gamma-B7 is a protein that in humans is encoded by the PCDHGB7 gene. This gene is a member of the protocadherin gamma gene cluster one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunog ...

                                               

PDE4D

The PDE4D gene is complex and has at least 9 different isoforms that encode functional proteins. These proteins degrade the second messenger cAMP, which is a key signal transduction molecule in multiple cell types, including vascular cells Domini ...

                                               

PDE6A

Rod cGMP-specific 3.5-cyclic phosphodiesterase subunit alpha is an enzyme that in humans is encoded by the PDE6A gene. PDE6A encodes the cyclic cGMP specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. ...