Blog page 164



                                               

FM (chemotherapy)

FM in the context of chemotherapy means a chemotherapy regimen used as first-line therapy in indolent lymphomas. In combination with rituximab it is called R-FM or RFM or FM-or FMR. The -FM regimen consists of: M itoxantrone - a synthetic anthrac ...

                                               

GemOx

GemOx or GEMOX is an acronym for one of the chemotherapy regimens used in the treatment of relapsed or primary refractory non-Hodgkins lymphoma and Hodgkins lymphoma. When combined with Rituximab it is called R-GemOx, R-GEMOX or GemOx-R, GEMOX-R. ...

                                               

GVD (chemotherapy)

GVD is a chemotherapy regimen, used for salvage treatment of relapsed or refractory Hodgkin disease, including those patients who relapse after stem cell transplantation. GVD regimen consists of three drugs: V inorelbine D oxil - pegylated liposo ...

                                               

Hyper-CVAD

Hyper-CVAD chemotherapy consists of two combinations of drugs courses A and B given in an alternating fashion. The term hyper refers to the hyperfractionated nature of the chemotherapy, which is given in smaller doses, more frequently, to minimiz ...

                                               

ICE (chemotherapy)

ICE in the context of chemotherapy is an acronym for one of the chemotherapy regimens, used in salvage treatment of relapsed or refractory non-Hodgkins lymphoma and Hodgkin lymphoma. In case of CD20-positive B cell lymphoid malignancies the ICE r ...

                                               

IMEP (chemotherapy)

IMEP is a chemotherapy regimen that is effective for nasal NK- / T-cell lymphoma. This chemotherapy regimen was also tested in Hodgkin disease as a part of a multidrug alternating scheme COPP / ABV / IMEP. But in that setting it showed no advanta ...

                                               

MINE (chemotherapy)

MINE in the context of chemotherapy is an acronym for one of the chemotherapy regimens used for treatment of relapsed or refractory aggressive non-Hodgkins lymphoma and Hodgkins lymphoma. Today this regimen is often combined with monoclonal antib ...

                                               

R-HDAC

R-HDAC, or R-HD-AraC ituximab plus igh ose ra-) is a chemotherapy regimen that is used, alternating with R-Maxi-CHOP, as part of so-called "Nordic protocol" of treating mantle cell lymphoma. It consists of monoclonal antibody rituximab and high-d ...

                                               

Sequential high-dose chemotherapy

Sequential high-dose chemotherapy is a chemotherapy regimen consisting of several sequential monochemotherapies with only one chemotherapeutic agent per course. The idea behind this approach is that when using single-agent chemotherapy, the docto ...

                                               

Stanford V

Stanford V is a chemotherapy regimen intended as a first-line treatment for Hodgkin lymphoma. The regimen was developed in 1988, with the objective of maintaining a high remission rate while reducing the incidence of acute and long term toxicity, ...

                                               

Nodular lymphocyte predominant Hodgkin lymphoma

Nodular lymphocyte predominant Hodgkin lymphoma is an indolent CD20 form of lymphoma. Some people no longer classified it as a form of classic Hodgkin lymphoma HL. This is because the Reed-Sternberg cell RSC variants popcorn cells that characteri ...

                                               

Follicular lymphoma

Follicular lymphoma is a cancer that involves certain types of white blood cells known as lymphocytes. The cancer originates from the uncontrolled division of specific types of B-cells known as centrocytes and centroblasts. These cells normally o ...

                                               

Large-cell lymphoma

The large-cell lymphomas have large cells. One classification system for lymphomas divides the diseases according to the size of the white blood cells that has turned cancerous. A large cell, in this context, has a diameter of 17 to 20 μm. Other ...

                                               

Mantle cell lymphoma

Mantle cell lymphoma is a type of non-Hodgkins lymphoma, comprising about 6% of NHL cases. There are only about 15.000 patients presently in the United States with mantle cell lymphoma. MCL is a subtype of B-cell lymphoma, due to CD5 positive ant ...

                                               

Peripheral T-cell lymphoma

Peripheral T-cell lymphoma refers to a group of T-cell lymphomas that develop away from the thymus. Examples include: Angioimmunoblastic T-cell lymphoma Subcutaneous panniculitis-like T-cell lymphoma Cutaneous T-cell lymphomas Peripheral T-cell l ...

                                               

Peripheral T-cell lymphoma not otherwise specified

Peripheral T-cell lymphoma not otherwise specified, is a subtype of peripheral T-cell lymphoma. Peripheral T-cell lymphoma is defined as a diverse group of aggressive lymphomas that develop from mature-stage white blood cells called T-cells and n ...

                                               

Splenic infarction

Splenic infarction is a condition in which blood flow supply to the spleen is compromised, leading to partial or complete infarction in the organ. Splenic infarction occurs when the splenic artery or one of its branches are occluded, for example ...

                                               

Splenosis

Splenosis is the result of spleen tissue breaking off the main organ and implanting at another site inside the body. This is called heterotopic autotransplantation of the spleen. It most commonly occurs as a result of traumatic splenic rupture or ...

                                               

Glycylcycline

Glycylcyclines are a class of antibiotics derived from tetracycline. These tetracycline analogues are specifically designed to overcome two common mechanisms of tetracycline resistance, namely resistance mediated by acquired efflux pumps and/or r ...

                                               

Midecamycin

Melting point vary depending on the compound type. It may also vary depending on the source consulted. Example: For the A 1 type: The Merck Index reports 155-156 Celsius. The Japanese Pharmacopoeia reports 153–158 Celsius. For the A 3 type: The M ...

                                               

Pikromycin

Pikromycin was studied by Brokmann and Hekel in 1951 and was the first antibiotic macrolide to be isolated. Pikromycin is synthesized through a type I polyketide synthase system in Streptomyces venezuelae, a species of Gram-positive bacterium in ...

                                               

Streptogramin A

Streptogramin A is a group of antibiotics within the larger family of antibiotics known as streptogramins. They are synthesized by the bacteria Streptomyces virginiae. The streptogramin family of antibiotics consists of two distinct groups: group ...

                                               

Ketolide antibiotics

                                               

Hypotensive transfusion reaction

A Hypotensive transfusion reaction or HTR is a rare condition that presents with low blood pressure associated with administration of blood products. The low blood pressure quickly resolves when the transfusion is stopped. HTRs are caused by the ...

                                               

Orthostatic syncope

Orthostatic syncope refers to syncope resulting from a postural decrease in blood pressure termed as Orthostatic hypotension. Orthostatic hypotension occurs when there is a persistent reduction in blood pressure of at least 20mmHg systolic or 10m ...

                                               

Atrial fibrillation with rapid ventricular response

Atrial fibrillation is an abnormal heart rhythm characterized by rapid and irregular beating of the atrial chambers of the heart. It often begins as short periods of abnormal beating which become longer or continuous over time. It may also start ...

                                               

Atrial fibrillation with rapid ventricular response

                                               

Atrioventricular block

Atrioventricular block is a type of heart block that occurs when the electrical signal traveling from the atria, or the upper chambers of the heart, to ventricles, or the lower chambers of the heart, is impaired. Normally, the sinoatrial node pro ...

                                               

Atrioventricular dyssynchrony

                                               

Atrioventricular reentrant tachycardia

Atrioventricular reentrant tachycardia, or atrioventricular reciprocating tachycardia, is a type of abnormal fast heart rhythm and is classified as a type of supraventricular tachycardia. AVRT is most commonly associated with Wolff–Parkinson–Whit ...

                                               

Automatic tachycardia

An automatic tachycardia is a cardiac arrhythmia which involves an area of the heart generating an abnormally fast rhythm, sometimes also called enhanced automaticity. These tachycardias, or fast heart rhythms, differ from reentrant tachycardias ...

                                               

AV nodal reentrant tachycardia

AV-nodal reentrant tachycardia is a type of abnormal fast heart rhythm. It is a type of supraventricular tachycardia, meaning that it originates from a location within the heart above the bundle of His. AV nodal reentrant tachycardia is the most ...

                                               

Bigeminy

Bigeminy is a heart rhythm problem in which there are repeated rhythms heart beats, one long and one shorter. Most often this is due to ectopic beats, or extra beats, occurring so frequently that there is one after each sinus beat, or normal rhyt ...

                                               

Cooper-Saeed waves

Cooper-Saeed waves refer to donor heart conducted P waves on the 12-lead ECG tracing of heart transplant recipients, also demonstrating nonconducted P waves of the recipient heart.

                                               

Ectopic focus

                                               

Ectopic focus

An ectopic pacemaker is an excitable group of cells that causes a premature heart beat outside the normally functioning SA node of the heart. It is thus a cardiac pacemaker that is ectopic, producing an ectopic beat. Acute occurrence is usually n ...

                                               

First-degree atrioventricular block

First-degree atrioventricular block is a disease of the electrical conduction system of the heart in which electrical impulses conduct from the cardiac atria to the ventricles through the atrioventricular node more slowly than normal. First degre ...

                                               

Heart block

Heart block is a disorder in the hearts rhythm due to a fault in the natural pacemaker. This is caused by an obstruction – a block – in the electrical conduction system of the heart. Sometimes a disorder can be inherited. Despite the severe-sound ...

                                               

Idioventricular rhythm

Normally, the pacemaker of the heart that is responsible for triggering each heart beat is the SA node. However, if the ventricle does not receive triggering signals at a rate high enough from either the SA node or the AV node, the ventricular my ...

                                               

Inappropriate sinus tachycardia

Inappropriate sinus tachycardia is a rare type of cardiac arrhythmia within the category of supraventricular tachycardia. IST may be caused by the sinus node itself having an abnormal structure or function, or it may be part of a problem called d ...

                                               

Junctional ectopic tachycardia

Junctional ectopic tachycardia is a rare syndrome of the heart that manifests in patients recovering from heart surgery. It is characterized by cardiac arrhythmia, or irregular beating of the heart, caused by abnormal conduction from or through t ...

                                               

Junctional escape beat

A junctional escape beat is a delayed heartbeat originating not from the atrium but from an ectopic focus somewhere in the atrioventricular junction. It occurs when the rate of depolarization of the sinoatrial node falls below the rate of the atr ...

                                               

Junctional rhythm

Junctional rhythm describes an abnormal heart rhythm resulting from impulses coming from a locus of tissue in the area of the atrioventricular node, the "junction" between atria and ventricles. Under normal conditions, the hearts sinoatrial node ...

                                               

Multifocal atrial tachycardia

Multifocal atrial tachycardia is an abnormal heart rhythm, specifically a type of supraventricular tachycardia, that is particularly common in older people and is associated with exacerbations of chronic obstructive pulmonary disease. Normally, t ...

                                               

J wave

A J wave - also known as Osborn wave, camel-hump sign, late delta wave, hathook junction, hypothermic wave, K wave, H wave or current of injury - is an abnormal electrocardiogram finding. J waves are positive deflections occurring at the junction ...

                                               

Paroxysmal supraventricular tachycardia

Paroxysmal supraventricular tachycardia is a type of supraventricular tachycardia, named for its intermittent episodes of abrupt onset and termination. Often people have no symptoms. Otherwise symptoms may include palpitations, feeling lightheade ...

                                               

Premature atrial contraction

Premature atrial contractions, also known as atrial premature complexes or atrial premature beats, are a common cardiac dysrhythmia characterized by premature heartbeats originating in the atria. While the sinoatrial node typically regulates the ...

                                               

Premature heart beat

A premature heart beat is a heart rhythm disorder corresponding to a premature contraction of one of the chambers of the heart. Premature heart beats come in two different types, premature atrial contractions and premature ventricular contraction ...

                                               

Premature junctional contraction

Premature junctional contractions, also called atrioventricular junctional premature complexes or junctional extrasystole, are premature cardiac electrical impulses originating from the atrioventricular node of the heart or "junction". This area ...

                                               

Premature ventricular contraction

A premature ventricular contraction is a relatively common event where the heartbeat is initiated by Purkinje fibers in the ventricles rather than by the sinoatrial node. PVCs may cause no symptoms or may be perceived as a "skipped beat" or felt ...

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